Salivary peptide histatin-1 aids in wound healing —

A study published online in The FASEB Journal delves into the mystifying fact that wounds in your mouth heal faster and more efficiently than wounds elsewhere. Until now, it was understood that saliva played a part in the wound healing process, though the extent of its role was unknown. The study examined the effects of salivary peptide histatin-1 on angiogenesis (blood vessel formation), which is critical to the efficiency of wound healing. Researchers found that histatin-1 promotes angiogenesis, as well as cell adhesion and migration.

“These findings open new alternatives to better understand the biology underlying the differences between oral and skin wound healing,” said Vicente A. Torres, Ph.D., associate professor at the Institute for Research in Dental Sciences within the Faculty of Dentistry at the University of Chile in Santiago, Chile. “We believe that the study could help the design of better approaches to improve wound healing in tissues other than the mouth.”

The study involved experiments at three levels: (1) endothelial, or blood vessel-forming, cells in culture, (2) chicken embryos as animal models, and (3) saliva samples obtained from healthy donors. Using these three models, histatin-1 and saliva were found to increase blood vessel formation. Researchers are now taking the next step in this line of study — using these molecules to generate materials and implants to aid in wound healing.

“The clear results of the present study open a wide door to a therapeutic advance. They also bring to mind the possible meaning of animals, and often children, ‘licking their wounds,'” said Thoru Pederson, Ph.D., Editor-in-Chief of The FASEB Journal.

Story Source:

Materials provided by Federation of American Societies for Experimental Biology. Note: Content may be edited for style and length.

credit : source

This entry Salivary peptide histatin-1 aids in wound healing — one of Dentine.info - Dental care information ideas and was posted on Thursday, May 17th, 2018 8:31 am. To explore more entry of the "Salivary peptide histatin-1 aids in wound healing —" you can browse these Dentistry or bowse by

Salivary peptide histatin-1 aids in wound healing —, the most important thing is dentist qualification. Make sure the dentist is licensed in the country where he or she practices. Look for his mandate, the dental school he graduated and their experience in this field. Salivary peptide histatin-1 aids in wound healing — It is very important to find the right dentist for your dental needs that you like. When looking for a good dental clinic, make sure you choose a place where you will receive the attention you need. Salivary peptide histatin-1 aids in wound healing — It needs to be opened comfortably and offers emergency and extended services to its patients. Low cost, affordable dental care and care at the dental office are equally important.